Ingredients & Science

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Why We Love the Ingredients in BrainBliss:

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  Supports cognitive clarity & focus (CBG + CBDV + Omega-3s)
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  Reduces neuroinflammation (CBD + GLA + Vitamin E)
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  Protects brain cells & prevents oxidative damage (Vitamin E + SDA + CBD)
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  Promotes neurotransmitter balance (CBD → serotonin; CBG → dopamine; Omega-3s → acetylcholine). Ahiflower oil enhances cannabinoid absorption, as cannabinoids require lipids for optimal bioavailability.
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  Vitamin E stabilizes Ahiflower oil & cannabinoids, preventing oxidation while enhancing cell membrane function.
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  CBD, CBG, and CBDV complement SDA & GLA by reducing inflammation, regulating neurotransmitters, and supporting neuroplasticity.

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Why We Love the Ingredients in BellyBalm:

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  Gut Lining Protection & Repair – Pumpkin Seed Oil + Vitamin E + CBDa
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  Anti-Inflammatory Effects – CBD + CBDa + CBG + Pumpkin Seed Oil
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  Supports Digestion & Motility – MCT Oil + CBG
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  Enhances Cannabinoid Absorption – MCT Oil + Pumpkin Seed Oil
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  Gut-Brain Axis Modulation – CBD + CBG + CBDa

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Why We Love the Ingredients in BodyBend:

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  Immune Support – CBD, CBG, CBC, Vitamin E, and Astaxanthin work together to modulate immune response, reduce inflammation, and improve immune cell function.
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  Antioxidant Defense – Astaxanthin and Vitamin E protect against oxidative damage, reducing the risk of cellular aging and promoting long-term health.
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  Neuroprotection – Astaxanthin, CBG, and CBC protect brain cells from oxidative stress while promoting neurogenesis and neuroplasticity.
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  Anti-Inflammatory Effects – CBD, CBG, and CBC support the reduction of chronic inflammation while promoting immune balance.
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  Enhanced Cannabinoid Absorption – MCT oil improves the bioavailability of cannabinoids and fat-soluble compounds (like Vitamin E and Astaxanthin).

Ahiflower is a plant-based omega oil that offers a complete & balanced source of essential fatty acids — omega 3-6-9 — making it an excellent choice for daily wellness routines without costing the earth through deriving these ingredients from fish.

Each acre of regeneratively grown Ahiflower produces as much omega-rich oil as 500,000 anchovies.

Ahiflower contains stearidonic acid (SDA), which is an efficient precursor to EPA, reducing neuroinflammation and supporting neurotransmitter function.

Gamma-linolenic acid (GLA) in Ahiflower is metabolized into DGLA (dihomo-γ-linolenic acid), which produces anti-inflammatory eicosanoids, protecting neurons from oxidative stress. Chronic inflammation is linked to cognitive decline, so reducing inflammation supports long-term brain health.

SDA and GLA help optimize the omega-3 to omega-6 balance, which helps regulate brain cell membrane integrity, optimizing neurotransmitter signaling, and influencing mood, focus, and memory.

Astaxanthin is a reddish pigment that belongs to a group of chemicals called carotenoid and is found in Micro-algae. The primary natural source is Haematococcus pluvialis, a micro algae. Our natural astaxanthin is grown and harvested in Moses Lake, Washington, USA and Gustavsberg, Sweden.

It's known for its potent antioxidant and anti-inflammatory abilities. Astaxanthin supports muscle recovery from exercise by depositing in muscle mitochondria to help to maintain blood glucose levels, promote fat utilization for energy, combat oxidative damage to muscle tissue as well as exercise-induced systemic inflammation.

Potent Antioxidant & Immune Modulator

• It is one of the most potent antioxidants available, with up to 6000 times more antioxidant power than Vitamin C, providing strong protection against oxidative stress and inflammation.
• It crosses the blood-brain barrier, offering neuroprotective effects alongside its ability to support skin health and reduce signs of aging.
• It has shown to help with immune function by modulating the activity of immune cells like T-cells, B-cells, and macrophages.
• Helps reduce inflammation in the body, enhancing the overall effects of CBD, CBG, and CBC.

Cannabinoids, which are chemical compounds found in cannabis, exert their effects by interacting with the body's endocannabinoid system (ECS). This system includes receptors (primarily CB1 and CB2) and endocannabinoids (natural compounds produced by the body) that help regulate various physiological processes. Cannabinoids can bind to these receptors, influencing functions such as pain, mood, memory, appetite, and immune response.

Cannabinoids act like keys, unlocking specific receptors in the body. This interaction influences various physiological processes, contributing to overall well-being.

Cannabidiol (CBD) is a chemical compound found in the cannabis plant that has gained attention for its potential therapeutic benefits. Unlike the psychoactive component of cannabis, CBD does not produce a "high". CBD has been studied for its potential to treat a variety of conditions, including epilepsy, anxiety, pain, and sleep disturbances. It interacts with the body's endocannabinoid system, potentially influencing mood, pain perception, and inflammation.

Neuroprotective & Anti-Inflammatory

• Activates CB1 & CB2 receptors, reducing neuroinflammation.
• Modulates glutamate and serotonin for improved mood, focus, and anxiety regulation.
• Enhances brain-derived neurotrophic factor (BDNF), supporting neuroplasticity (critical for learning & memory).

Gut-Brain Axis & Anti-Inflammatory Support

• Modulates CB1 & CB2 receptors in the gut, reducing intestinal inflammation and gut permeability (leaky gut syndrome).
• Supports gut motility—helpful for bloating, cramping, and irregular digestion.
• May reduce visceral hypersensitivity, potentially beneficial for IBS and IBD symptoms.
• Works with MCT oil for enhanced absorption and faster onset.

The cannabis plant contains many substances known as cannabinoids. Both CBDA and CBD are cannabinoids, with CBDA being the precursor of CBD. Both chemicals are similar, but they interact with the body in different ways. Unlike CBD, CBDA does not directly bind to endocannabinoid receptors but instead inhibits certain enzymes.

CBDA and CBD can work together, and when this happens, researchers call it an entourage effect. An entourage effect occurs when the inactive parts of the cannabis plant help enhance the effect of the more active parts.

Potent Anti-Inflammatory & Nausea Relief

• Strong COX-2 inhibitor—reduces gut inflammation without suppressing protective COX-1 (safer for gut lining than NSAIDs).
• More bioavailable than CBD, meaning even lower doses can be effective.
• Anti-nausea effects via serotonin receptor modulation (5-HT1A), beneficial for gut-brain signaling.
• Supports gut microbiome balance and reduces excessive immune activation in the intestines.

CBC is non-intoxicating because it binds poorly to CB1 cannabinoid receptors in the brain. But CBC does bind with other receptors in the body, such as the vanilloid receptor 1 (TRPV1) and transient receptor potential ankyrin 1 (TRPA1), both of which are linked to pain perception. When CBC activates these receptors, increased levels of the body's natural endocannabinoids like anandamide are released.

Immune Modulation & Neuroprotective Benefits

• CBC works by promoting immune balance, reducing inflammation, and enhancing the function of the CB2 receptors, which are key for immune system regulation.
• CBC also has neuroprotective properties, supporting brain health, reducing oxidative stress in neurons, and enhancing neurogenesis (the growth of new brain cells).
• Works synergistically with CBD and CBG to enhance anti-inflammatory and immune-modulating effects.

CBDV is an intriguing cannabinoid with a distinctive interaction profile in the body, offering potential therapeutic benefits, particularly in neurological and muscular conditions.

CBDV shows a low affinity for CB1 and CB2 receptors, indicating a distinct mode of interaction within the endocannabinoid system. However, it is a more potent and efficacious agonist at the CB2 receptor. These interactions suggest CBDV's potential to modulate physiological responses without the intoxicating effects associated with high-affinity CB1 receptor agonists like THC.

Anti-Inflammatory & Neuroplasticity

• Modulates TRPV1 & TRPA1 channels, involved in neural excitability & sensory processing.
• Shows potential in supporting neurodevelopmental conditions (e.g., epilepsy, autism).
• Enhances GABAergic activity, contributing to calm focus without sedation.

Cannabigerol (CBG) is a non-psychoactive cannabinoid, a minor constituent of cannabis, and one of over 120 identified cannabinoids in the Cannabis plant genus. It is the decarboxylated form of cannabigerolic acid (CBGA), the parent molecule from which other cannabinoids are biosynthesized.

During plant growth, most CBG converts to other cannabinoids, mainly tetrahydrocannabinol (THC) or cannabidiol (CBD). This leaves approximately 1% CBG in the final plant material. However, some strains are cultivated to produce higher amounts of CBG and CBGA, with lower quantities of other cannabinoids.

Neurogenic & Dopaminergic Support

• Enhances anandamide signaling (the "bliss molecule"), promoting mental clarity and emotional balance.
• Interacts with α2-adrenergic receptors, which influence dopamine regulation—key for motivation and cognitive processing.
• Has antioxidant and neurogenic properties, potentially supporting neuron regeneration.

Gut Motility & Microbiome Balance

• Antimicrobial properties—CBG may help reduce pathogenic bacteria like E. coli while supporting beneficial gut bacteria.
• Interacts with alpha-2 adrenergic receptors, regulating gut motility (helpful for bloating & sluggish digestion).
• Neuroprotective for the enteric nervous system (ENS), supporting the gut-brain connection for stress-related GI issues.

Immune Modulation & Antimicrobial

• Known as the "mother of all cannabinoids," CBG supports immune modulation, promoting a healthy immune response without overstimulation.
• Enhances cannabinoid receptor activity to help reduce symptoms of conditions like inflammatory bowel disease (IBD) and other immune disorders.

Medium-chain triglycerides (MCTs) are fats found in foods like coconut oil. They're metabolized differently from the long-chain triglycerides (LCT) found in most other foods.

MCT oil is a supplement that contains a lot of these types of fats. Triglyceride is simply the technical term for fat. Triglycerides have two main purposes. They're either burned for energy or stored as body fat.

Because of their shorter length, MCTs are absorbed more quickly by the body and don't require as much digestion as other fats. They are transported to the liver, where they are converted into ketones, a source of energy.

• Cognitive Support – MCTs, particularly caprylic and capric acid, may help improve brain function in aging dogs and those with cognitive decline.
• Energy Boost – MCTs are rapidly absorbed and converted into ketones, providing a quick energy source without relying on glucose.
• Skin & Coat Health – May help with dry skin, itchiness, and maintaining a healthy coat due to its moisturizing and anti-inflammatory properties. Improves nutrients absorption of fat soluble vitamins which are crucial for skin and coat health.
• Digestive Health – Easier to digest than long-chain fats, MCTs can help dogs with malabsorption issues or inflammatory gut conditions.
• Seizure Management – Some studies suggest MCT oil (especially ketogenic diets with MCTs) may help reduce seizure frequency in dogs with epilepsy.
• Easily digestible fat that bypasses typical fat digestion and is quickly absorbed for energy.
• Has antimicrobial properties (caprylic acid & capric acid) that may help reduce harmful gut bacteria while supporting beneficial flora.
• Helps carry and enhance the bioavailability of fat-soluble cannabinoids (CBD, CBG, CBDa) and Vitamin E.
• Enhances the bioavailability of fat-soluble compounds like cannabinoids (CBD, CBG, CBC) and Astaxanthin for greater effectiveness.

Pumpkin seed oil is cold pressed from pumpkin seeds for a range of culinary and cosmetic uses. Its nutty flavor makes it a favorite in desserts, salad dressings, and a finishing oil for dishes. It's also offered as a treatment for healthy hair and skin.

Researchers are also exploring pumpkin seed oil's ability to heal wounds. Studies have been conducted using rodents, but further research into the effects on humans is needed. Pumpkin seeds are high in antioxidants that help your body fight off disease. Their anti-inflammatory properties are also being studied. Pumpkin seed oil is believed to support digestive health due to its anti-inflammatory properties and high fatty acid content. It may help soothe the gastrointestinal tract, alleviate symptoms of conditions like irritable bowel syndrome (IBS), and promote regular bowel movements.

Gut Barrier & Anti-Inflammatory Support

• Rich in omega-6 (linoleic acid) and omega-9 (oleic acid), which support gut lining integrity.
• Contains phytosterols & antioxidants, which may reduce gut inflammation and oxidative stress.
• High in zinc & magnesium, essential for gut healing & digestive enzyme function.
• Can soothe irritable bowel symptoms and support regular bowel movements.

Vitamin E is a nutrient that's important for vision, fighting off diseases and the health of the blood, brain, and skin.

Vitamin E is an antioxidant. Antioxidants might protect cells from the effects of free radicals, which are molecules made when the body breaks down food or is in contact with tobacco smoke or radiation. These molecules might lead to heart disease, cancer, and other diseases.

Foods rich in vitamin E include vegetable oils such as canola and olive oils, nuts, and seeds. Meats, dairy, leafy greens, and fortified cereals also have vitamin E.

• It is a powerful fat-soluble antioxidant that prevents lipid peroxidation in the brain.
• This is especially relevant because omega-3s in Ahiflower are prone to oxidation—Vitamin E helps preserve their structure and function.
• Supports mitochondrial health in neurons, reducing oxidative stress and supporting cognitive function.
• Helps stabilize Pumpkin Seed Oil and MCT oil, preventing oxidation.
• Protects gut lining cells from oxidative damage, supporting intestinal barrier integrity.
• Works with cannabinoids to reduce gut inflammation and support microbiome balance.
• Works synergistically with Astaxanthin to further protect against oxidative stress, promoting cellular health and longevity.

• Blood and tissue docosahexaenoic acid (DHA, 22:6n-3) turnover rates from Ahiflower® oil are not different than from DHA ethyl ester oil in a diet switch mouse model
• Ahiflower Supports Gut Microbiome Balance & Promotes Overall Anti-inflammatory Status
• Ahiflower is a Recognized Anti-neuroinflammatory Synergist in Boosting Cognitive Performance
• Ahiflower Boosts EPA Levels & Anti-inflammatory Status Efficiently

• Astaxanthin uptake in domestic dogs and cats
• Effects of astaxanthin supplementation in healthy and obese dogs

• A 2022 Systematic Review and Meta-Analysis of Enriched Therapeutic Diets and Nutraceuticals in Canine and Feline Osteoarthritis
• The role of cannabinoids in pain modulation in companion animals
• Preliminary Investigation of the Safety of Escalating Cannabinoid Doses in Healthy Dogs

• The Modulatory Effects and Therapeutic Potential of Cannabidiol in the Gut
• Localization of cannabinoid receptors CB1, CB2, GPR55, and PPARα in the canine gastrointestinal tract
• A randomized, double-blind, placebo-controlled study of daily cannabidiol for the treatment of canine osteoarthritis pain

• Pharmacokinetics, efficacy, and safety of cannabidiol in dogs: an update of current knowledge
• Evaluation of repeated or acute treatment with cannabidiol (CBD), cannabidiolic acid (CBDA) or CBDA methyl ester (HU-580) on nausea and/or vomiting in rats and shrews
• Cannabinoid Regulation of Acute and Anticipatory Nausea

• The Mechanism of Cannabichromene and Cannabidiol Alone Versus in Combination in the Alleviation of Arthritis-Related Inflammation
• Toxicological Evaluation and Pain Assessment of Four Minor Cannabinoids Following 14-Day Oral Administration in Rats

• Cannabidivarin alleviates neuroinflammation by targeting TLR4 co-receptor MD2 and improves morphine-mediated analgesia
• Cannabidivarin mitigates motor and cognitive impairments in a female mouse model of Rett syndrome

• Single dose and chronic oral administration of cannabigerol and cannabigerolic acid-rich hemp extract in fed and fasted dogs: Physiological effect and pharmacokinetic evaluation
• Safety study of cannabidiol products in healthy dogs
• Acute effects of cannabigerol on anxiety, stress, and mood: a double-blind, placebo-controlled, crossover, field trial
• Cannabigerol as an anti-inflammatory agent altering the level of arachidonic acid derivatives in the colon tissue of rats subjected to a high-fat high-sucrose diet

• Oral Palatability Testing of a Medium-Chain Triglyceride Oil Supplement (MCT) in a Cohort of Healthy Dogs in a Non-Clinical Setting
• Efficacy of a Therapeutic Diet on Dogs With Signs of Cognitive Dysfunction Syndrome (CDS): A Prospective Double Blinded Placebo Controlled Clinical Study
• Feeding healthy beagles medium-chain triglycerides, fish oil, and carnitine offsets age-related changes in serum fatty acids and carnitine metabolites

• The potential of pumpkin seed oil as a functional food-A comprehensive review of chemical composition, health benefits, and safety
• Nutraceutical Impact of Pumpkin Seed Oil on Expression Levels of EZH-2 and KRT-14 Genes against DSS-induced Inflammatory Bowel Disease in the Rat Model

• Association between vitamin E and enhanced athletic performance in sled dogs
• Evaluation of Total Antioxidant Activity and Oxidative Stress in Seminal Plasma from Dogs Supplemented with Fish Oil and Vitamin E
• Improvement of short-term memory performance in aged beagles by a nutraceutical supplement containing phosphatidylserine, Ginkgo biloba, vitamin E, and pyridoxine
• Safety and pharmacokinetic studies of liposomal antioxidant formulations containing N-acetylcysteine, α-tocopherol or γ-tocopherol in beagle dogs